Showing posts with label immunosuppressants. Show all posts
Showing posts with label immunosuppressants. Show all posts

Wednesday, April 29, 2009

Increase in immunosuppressant levels

I took these pictures with my cellphone after my appointment at the research clinic.  It was a beautiful day, so I took my usual walk along the Mississippi river.  

I returned home from my visit to Minneapolis on Tuesday evening.  On Wednesday, I got a phone call saying that my drug levels were too low and I needed to make a significant increase in both.  

Unfortunately, the increase has caused me to practically start over with the adjustment period with the new drugs.  I was tired, nauseated, and had a terrible headache.  By Friday, the nausea was bad enough that I was afraid I might have to leave work, so I called and spoke with Dr. Bellin.  She suggested trying Tums.  I did and they worked surprisingly well.  It got me through the day and has helped me get through the rough spots.

I have been slowly getting better as the days go by, but my stomach still bothers me a lot.  I am hoping that time will help me get through this as it did before.  It is easier the second time around.  I don't have the fear that this might be permanent like I did before.  I also know from the bloodwork done at my visit that I am not dehydrated or out of synch in my body chemistries.

The good news was that my C-peptide numbers were great.  My fasting was 1.27 and my postprandial was 5.29.
More evidence that my cells are happy with these crazy new drugs.

Saturday, April 11, 2009

New drug issues continued...

I am now finished with the Raptiva/Rapamune drug regimen.  They should soon be out of my system and I can see how the new drugs are treating me.  I  think that my energy level is better, but my stomach is still uncomfortable.  I have been taking Metamucil, but it has not helped much.  I miss my coffee.  It just doesn't sound good anymore.

Most importantly, my blood sugar levels have been good.  I have had a few higher ones since I started the new drugs, but they seem to be getting fewer and not as high.

I suppose that having side effects of the immunosuppressants like I am having now is more what I expected pre-transplant.  I think that I was just very lucky with the first set.  Hopefully, the Prograff and Cellcept will settle down somewhat, but all that really matters is that they protect my islet cells.