It was an interesting experience. I was hooked up to two IVs. One delivered the glucose and then the insulin, and the other was used to draw blood samples. I was drawn at each of these intervals and the blood was sent to the lab to be tested for C-peptide (measures islet cell function), glucose, and insulin.
After a baseline was established, I was given a giant bolus of glucose. The nurse warned me that it would make me feel flushed and light-headed and it did both of those. As you can see, my glucose rose dramatically. My insulin level increased as did my C-peptide, proving that my islet cells were responding to the high glucose level in my blood.
Next I was given a bolus of insulin. It was a calculated dose, and I think it was about 2.5 units. It was kind of scary to get that much. It had been so long since I have had an insulin injection and I was worried about going too low, but it went very smoothly. My insulin level rose quickly and then tapered off after bringing my glucose level back to normal. My C-peptide also decreased as the insulin level decreased.
I am not sure what kind of results a nondiabetic person might yield. I assume it is close to these results. My islets seem to be functioning well. It still is such an exciting experience and is so rewarding to see results like this. I still test my glucose before and after each meal and at bedtime, and I get a charge every time I see all of my nice normal numbers.
i just ran across your post. I am a Type 1 (recent, just last 3-4 years) and am active in the cell therapy industry. I will be keeping up with your blog to check out your progress.
Good luck with your new Islets!
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